Chromosomal Microarray Analysis (CMA)
Chromosomal microarray analysis (CMA) is recommended for analyzing cytogenic variations in patients suffering for unexplained developmental delays, intellectual disabilities, autism spectrum disorders, and/or multiple congenital malformations.
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Cytogenic variations are known to cause a broad range of developmental disorders, primarily neurodevelopmental and congenital anomalies.
Chromosomal microarray analysis (CMA)
- As a first-step analysis for cases of unexplained developmental delays, intellectual disabilities, autism spectrum disorders, and/or multiple congenital malformations
- For deletion/duplication analysis of extremely large genes where gross deletions involving large segments of genes, flanking intergenic regions, or neighboring genes are frequently reported
- To diagnose uniparental disomy (UPD) and regions exhibiting loss/absence of heterozygosity (LOH)
- In conjunction with whole exome sequencing (CentoXome) to complement large CNVs. CentoArray can be ordered either as a step-wise analysis after CentoXome or together as a single-step approach
- For prenatal testing to help determine a cause of ultrasound-detected abnormalities via CentoArray Prenatal
Our CMA Platform designed to represent latest clinical and genetic insights with more than 4,800 cytogenic relevant genes based on ClinGen, DDG2P, ClinVar, PharmGKB, NHGRI-EBI, and GWAS database
Chromosomal microarray analysis (CMA)
is recommended for analyzing cytogenic variations in patients suffering for unexplained developmental delays, intellectual disabilities, autism spectrum disorders, and/or multiple congenital malformations.
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