Chromosomal Microarray Analysis

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Chromosomal Microarray Analysis (CMA)

Chromosomal microarray analysis (CMA) is recommended for analyzing cytogenic variations in patients suffering for unexplained developmental delays, intellectual disabilities, autism spectrum disorders, and/or multiple congenital malformations.


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Cytogenic variations are known to cause a broad range of developmental disorders, primarily neurodevelopmental and congenital anomalies.



HIGH RESOLUTION AND BROAD COVERAGE

Optimized probe spacing, focusing on exonic regions to provide the best cytogenetic disease variant coverage




DISEASE-FOCUSED CONTENT

Platform designed to represent latest clinical and genetic insights based on ClinGen, DDG2P, ClinVar, PharmGKB, NHGRI-EBI, and GWAS database




QUALITY ANALYSIS

Delivering high-quality analysis via extensive genome-wide cytogenetic analyisis to detect structural aberrations, such as CNVs, chromosomal imbalances, LOH, UPD, and mosaicism




WIDE RANGE OF SAMPLE TYPES

CentoCard®, EDTA blood, ready to use DNA, buccal swab, chronic villi, and amniotic fluid




Testing with CentoArray®

Built on the latest genetic and medical insights. Covering more than 4,800 cytogenetic relevant genes with exon level resolution.




Early and accurate answers

Short turnaround time of 15 business days


what you should know about

Chromosomal microarray analysis (CMA)

  • As a first-step analysis for cases of unexplained developmental delays, intellectual disabilities, autism spectrum disorders, and/or multiple congenital malformations
  • For deletion/duplication analysis of extremely large genes where gross deletions involving large segments of genes, flanking intergenic regions, or neighboring genes are frequently reported
  • To diagnose uniparental disomy (UPD) and regions exhibiting loss/absence of heterozygosity (LOH)
  • In conjunction with whole exome sequencing (CentoXome) to complement large CNVs. CentoArray can be ordered either as a step-wise analysis after CentoXome or together as a single-step approach
  • For prenatal testing to help determine a cause of ultrasound-detected abnormalities via CentoArray Prenatal

Our CMA Platform designed to represent latest clinical and genetic insights with more than 4,800 cytogenic relevant genes based on ClinGen, DDG2P, ClinVar, PharmGKB, NHGRI-EBI, and GWAS database

Chromosomal microarray analysis (CMA)

 is recommended for analyzing cytogenic variations in patients suffering for unexplained developmental delays, intellectual disabilities, autism spectrum disorders, and/or multiple congenital malformations.

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